terça-feira, 29 de janeiro de 2008

Dr. Walter França

O Dr. Walter França; Formado em 1976 pela Faculdade de Ciências Medicas de Pernambuco; Membro Titular da Sociedade Brasileira de Cirurgia Bariátrica; Vice Delegado - Recife da Sociedade Brasileira de Cirurgia Bariátrica; Membro Titular da Sociedade Brasileira de Cirurgia Videolaparoscópica; Membro Titular do Colégio Brasileiro de Cirurgiões; Preceptor de Ensino da Disciplina de Cirurgia Abdominal da UPE; Cirugião do programa de Cirurgia Bariatrica do Hospital Osvaldo Cruz; Chefe da Cirurgia de Urgência do Hospital Jaime da Fonte; Membro do Conselho Regional de Medicina de Pernambuco;Ex - Chefe do programa de Cirurgia Bariatrica do Hospital da Polícia Militar de Pernambuco; juntamente com sua equipe (composta de Psicólogos, Nutricionistas, Anestesistas) está na vanguarda do combate a obesidade mórbida através das cirurgias bariáticas.

fonte: http://www.walterfranca.com.br/home/

3 comentários:

ileana disse...

Caro Dr.. Lá algo que eu quero compartilhar com você da tomada um olhar desta.

Randomized Controlled Study Confirms MonaVie Active(TM) Acai Juice has High Antioxidant Capacity
2007-10-09 - MonaVie

Results To Be Presented At Fruits and Vegetables Health 2007 Conference

PUYALLUP, WA, October 9, 2007 - The results of recent research surrounding MonaVie Active(TM), a juice containing acai berries and pulp, as well as other nutrient-rich fruits, will be presented in a session entitled "Antioxidants in Fruits and Vegetables and Improving Human Health" at the 2nd International Symposium on Human Health Effects of Fruits and Vegetables on Wednesday, October 10, 2007, 10:15 a.m. - noon, in the Grand Salon East at the Omni Hotel in Houston, TX. Alexander Schauss, PhD, FACN, will highlight findings of in vitro studies evaluating the antioxidant capacity of MonaVie, as well as in vivo studies to determine antioxidant absorption and bioactivity.
This three-part study examined whether the fruit antioxidants in MonaVie are in a form able to enter into and protect living cells in vitro and also examined the bioavailability of MonaVie and its effect on serum biomarkers of oxidative damage after ingestion. An initial in vitro study was performed to evaluate the antioxidant capacity of MonaVie in a cell-based antioxidant capacity (CAP) assay, as well as using the TEAC assay that found it to be 28,421 umolTE/L. MonaVie showed a clear dose-dependent antioxidant effect in the CAP assay, indicating that compounds in MonaVie are able to cross the plasma membrane of living cells and subsequently provide significant protection from oxidative damage within the cells.
In the second stage of the study, four ounces of MonaVie was administered to six participants on a single day to identify the time course for antioxidant absorption and bioactivity. Blood samples were collected immediately prior to ingestion and at 30, 60 and 120 minutes post consumption. Evidence of absorption, based on increased antioxidant bioactivity and antioxidant compounds in serum was found in all six subjects. A third randomized, double-blind, placebo-controlled, cross-over study of 12 healthy adults was then conducted. Participants fasted overnight and a baseline blood sample was drawn. Immediately afterward, four ounces of MonaVie or a placebo was consumed. Blood samples were drawn at one and two hours after ingestion, and CAP and thiobarbituric acid reactive substances (TBARS) assays were used to evaluate serum antioxidant capacity and serum lipid peroxidation, respectively. Consumption of MonaVie resulted in an increase in the serum antioxidant capacity in 11 of 12 participants within two hours of consumption. Results also found that ingestion of MonaVie resulted in a decrease in serum lipid peroxidation within two hours of consumption in 10 of the 12 study participants, most likely due to the increased serum antioxidant capacity.
Alexander G. Schauss, PhD, FACN, senior director of natural and medicinal products research for AIBMR Life Sciences, has held faculty appointments at four institutions of higher learning, including that of associate professor of behavioral sciences, associate professor of research, clinical professor of natural products research and adjunct research clinical professor of botanical medicine. He now concentrates on research. In 2005, he was the recipient of the Linus Pauling Lecture Award from the American College for the Advancement of Medicine for "contributions to the medical sciences." The author of 12 books on health and nutrition, and the senior co-author of four others, Dr. Schauss lives in Tacoma, Wash.
Founded in January 2005 and headquartered in Salt Lake City, Utah, MonaVie develops and markets scientifically formulated, premium quality nutritional juices. The company's flagship product, MonaVie Active(TM), is a proprietary blend of the acai berry, which independent studies have shown has the highest antioxidant activity of any fruit or vegetable in vitro, and other nutrient-dense fruits including pomegranate, goji berry, camu camu, passion fruit, aronia, acerola, bilberry, blueberry, apricot, purple grape, white grape, nashi pear, lychee, banana, kiwi, pear, cranberry and prune, each selected for its unique, beneficial properties. Acai contains concentrated levels of anthocyanins, a powerful family of antioxidants that assist in neutralizing harmful free radicals. The acai berries used to make MonaVie are processed in a cGMP, ISO certified and U.S. FDA-inspected food manufacturing facility in Brazil. For more information visit www.monavie.com.
The 2nd International Symposium on Human Health Effects of Fruit and Vegetables provides a forum for horticultural scientists, nutritionists, food scientists, biomedical scientists, chemists, biochemists, clinicians, medical professionals and social economists to exchange information and bridge the communication gap between the agricultural sciences, nutrition and health sciences. This symposium, sponsored by the 2nd International Society for Horticultural Sciences (ISHS) and Texas A&M's Vegetable and Fruit Improvement Center (VFIC) and Center for Obesity Research and Program Evaluation (CORPE), will focus on cultural and genotypic factors affecting the content of bioactive compounds in fruits and vegetables, and will cover a wide range of topics related to the characterization, pharmacokinetics, nutrition and human health clinical aspects of fruits and vegetables. For more information visit http://favhealth2007.tamu.edu/index.htm.
# # #
Dr. Alex Schauss
AIBMR Life Sciences
P: 253-286-2888

Related Articles :
• Açaí - Potent Antioxidant Superfruit (2007-01-08)
The second in our mini-series of reviews covering the nutrient rich super-fruits currently receiving a lot of attention, provided us by Dr. Paul Gross (www.berrydoctor.com). Here we feature the Açaí Berry and will follow it up in upcoming months with additional berries and fruits.
• Anheuser-Busch Unlocks the Mystery of the Goji Berry (2007-02-26)
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ileana disse...

Prezados Amigos,
É com profunda gratidão que lhes dou as boas-vindas à MonaVie para integrar nossa família em BOAS VINDAS
crescimento no Brasil! Desde o inicio da MonaVie, em 2005, tenho esperado pelo dia em que poderíamos trazer, a vocês, maravilhosos cidadãos brasileiros, este produto e esta oportunidade incríveis. Para mim, é como se fosse uma volta para casa. Nossas origens se encontram profundamente enraizadas em seu imenso país, e eu me sinto pessoalmente comprometido com o seu sucesso.
Quando lançamos o MonaVie nos Estados Unidos, milhares de pessoas começaram a se envolver durante a fase de pré-lançamento, porque elas percebiam uma oportunidade única daquela que, certamente, seria uma empresa grande e bem sucedida. Eu os incentivo a aproveitar a vantagem da oportunidade de pré-lançamento e começar a construir a sua organização hoje mesmo.
Mais uma vez, bem-vindos à MonaVie! Espero encontrá-los brevemente.
Calorosas saudações
Dallin A. Larsen
Fundador e Presidente

Cadastre-se na Monavie
Registre-se agora durante o pre-lancamento da Monavie no Brasil e garanta o seu lugar hoje!
Cadastre-se na MONAVIE Por favor entre com o ID
de seu patrocinador no espaço abaixo.
Id # 441147
Ileana & Orlando Perez
1(352)307-4605 EU

Mona Vie disse...

Açaí - Potent Antioxidant Superfruit
2007-01-08 - Paul M. Gross, PhD

Paul M. Gross, PhD
Just by its deep violet color, you know there is something special about açaí, the tropical palmberry (Euterpe oleraceae Mart.). With pigmentation so dense, its juice stains anything it touches – skin, cowhide, containers, even teeth when frequently taken undiluted.

Used for food, beverages, medicines and dyes by Amazon peasants over centuries, açaí has blazed its way into popularity on the US market over recent years as one of Nature's superfruits with a delicious taste and versatility of beverage and food applications.

Until recently, however, this reputation was based on assumptions that such a legendary and richly pigmented fruit would be nutritious and have exceptional antioxidant properties. Due to the remoteness and obscurity of açaí, and its highly perishable nature, no contract laboratory assays were available and there were few scientific studies in the medical or food science literature.

Even at the end of 2006, there were only 10 medical reports on açaí listed in PubMed, the online database of medical publications by the US National Library of Medicine (http://pubmed.gov).

However, two recent research publications and one contract assay have supplied new information about açaí that allows comparisons with other better-known nutritious, antioxidant fruits -- in this example, goji (“wolfberry”) and blueberry. Below is a summary of these new findings.

Nutrient Content

Upon review of the tables below are several new facts about the nutrient content of açaí. As the assessment of this berry's nutritional composition comes from two sources (4,7) whose açaí samples were not identical, average or approximated data are presented:
1. the caloric value of a single serving (approximately 600 calories per standard 100 g) is exceptional among comparative berry fruit such as goji (“wolfberry”, Lycium barbarum L.) and lowbush blueberry (Vaccinium angustifolium L.), apparently due to its remarkably high fat content
2. the total fat content for açaí berry is highly unusual for fruit, some 40% of dry weight

3. it has a very high fiber content, approximately 35%

4. relative to the National Academy of Sciences (NAS) Dietary Reference Intakes (DRI) and the micronutrient-dense goji berry, açaí has remarkable contents of several essential minerals – calcium, copper, iron, magnesium, phosphorus, potassium and zinc

5. lipid-soluble antioxidant vitamins A and E are rich in concentration, 1000 IU and 45 mg per 100 g, respectively. 67% of the total tocopherols in açaí pulp are alpha-tocopherol (4).

Table 1. Macronutrients

(1) Laboratorio Catarinense SA, Joinville, Brazil, ref. 4
(2) Schauss et al., ref. 7
(3) Gross et al., ref. 3
(4) ref. 1

By comparison with the two other berry species shown - goji and blueberries - the new açaí analyses demonstrate a much higher energy, fat and fiber yield. By comparison to most plant foods, goji berry is also a high-calorie, nutrient-dense fruit, whereas blueberry is relatively lean in caloric value and nutrients.

Analysis of the fat composition by both sources (4,7) revealed the precise origins of açaí's exceptional lipid density. Nearly all of the saturated fatty acid content in açaí is from palmitic acid (IUPAC hexadecanoic acid, approx. 23%), monounsaturated fat is from oleic acid (approx. 58%, an omega-9 fat,18:1 ω-9), and polyunsaturated fats result from linoleic acid (12%, an omega-6 fat, 18:2 ω-6). These three fatty acids, therefore, make up 93% of the total lipids in açaí. The oleic acid content of açaí is the same as in olive oil.

A similar compartmental analysis of fiber sources was not completed in either study. Previously, analysis of high-fiber plant foods like Rubus and goji berries showed that pectins, lignans, cellulose and polysaccharides comprise the high fiber content of these fruits (3). It would be valuable to have such an assay done on açaí pulp as this fruit appears to be truly exceptional as a dietary fiber source.

Both assays included data for several phytosterols, plant-derived lipids with structure similar to mammalian cholesterol. Phytosterols have considerable promise as cholesterol-lowering and anticancer agents in human therapies (5). In each study, beta-sitosterol was the dominant element, comprising some 85% (average) of the total for all sterols (Table 2). These results reveal açaí as an enriched food source of this valuable phytosterol.

In summary, açaí fruit displays unusually high contents of calories, diverse fats, fiber and phytosterols, particularly beta-sitosterol.

The density of several minerals in açaí is a significant percentage of the DRI, especially for copper and zinc which equal or exceed the DRI (Table 2). In one assay (4), vitamin E content was 3-times the DRI (Table 2).

Table 2. Essential Micronutrients

(1) Laboratorio Catarinense SA, Joinville, Brazil, ref. 4
(2) Schauss et al., ref. 7
(3) Gross et al., ref. 3
(4) ref. 1
* not considered a micronutrient; x, no RDI established; ^ demonstrated in fruit, roots and leaves of Lycium barbarum L. or Lycium chinense (3); ? no reports

Phenolic Antioxidants

Attention of food chemists is drawn readily to açaí by its rich color, a subjective indication of high concentration of phenolic pigments with antioxidant properties that may convey health benefits for numerous human disease conditions (8,9).

Both studies (4,8) analyzed açaí pulp for phenolic compounds, finding levels of anthocyanins were1% of sample mass (4) and total phenolics unexpectedly moderate (1.4 g per 100 g, ref. 8). It is likely that phenolics not yet identified are present in açaí, indicating a need for further analysis of pigments in this intriguing berry.

In the study by Schauss and coworkers (8), measurements of oxygen radical absorbance capacity (“ORAC”, antioxidant strength) were performed on freeze-dried açaí pulp and skin powders in vitro for each of four reactive oxygen species (ROS) - superoxide, peroxynitrite, hydroxyl radical and peroxyl radical for both hydrophilic- and lipid-soluble species.

The assay for superoxide, considered perhaps the most representative determination of antioxidant capacity (as it is involved in formation of other ROS and circulates systemically in blood), revealed a value of 161,400 units per 100 g, the highest result yet found for superoxide radical among plant foods (8). Total ORAC (against peroxyl radical) determined from both hydrophilic and lipophilic sources was 102,700 units per 100 g, again the highest value found to date among edible fruits and vegetables for this radical (8). Additional evidence showed that açaí pulp significantly inhibited the formation of all ROS in vitro (8).

Research Directions, Commercial Development and Potential Health Effects.

To date, there has been limited research interest in açaí mainly due its novelty in food science, but this is certain to change in coming years. Appealing exotic foods with high antioxidant strength and rich nutrient content will undoubtedly attract scientific attention and find diverse applications in the functional food industry.

A potential problem in developing açaí for broader commercial purposes as a functional food is susceptibility to oxidation due to its exceptional fat content. This will be a significant challenge to prevent spoiling during post-harvest handling, processing and shipping. Freeze-drying of the fresh pulp is one solution that appears to effectively preserve nutrients (7,8).

Dozens of diseases have a component of oxidative stress at their origins, such as chronic inflammation, atherosclerosis, diabetes and cancer (8,9), and so may be prevented or inhibited by high-antioxidant fruit like açaí.

For example, a recent study showed that açaí antioxidants could induce more rapid death (apoptosis) of leukemia cells in vitro (2). This preliminary research indicates a possible anti-cancer effect of anthocyanins and other açaí pigments, similar to promising laboratory results examining phenolics in the black raspberry as a chemopreventive food source (6).

1. Blueberry Nutrients, World's Healthiest Foods,

2. Del Pozo-Insfran D, Percival SS, Talcott ST. Acai (Euterpe oleracea Mart.) polyphenolics in their glycoside and aglycone forms induce apoptosis of HL-60 leukemia cells. J Agric Food Chem. 2006 Feb 22;54(4):1222-9.
3. Gross PM, Zhang X, Zhang R, Wolfberry: Nature’s Bounty of Nutrition and Health, Booksurge Publishing (Amazon.com), 2006.
4. Laboratorio Catarinense SA, Joinville, Brazil and Markan Global Enterprises, http://thesuperberry.com/constituents.htm
5. Ling WH, Jones PJ. Dietary phytosterols: a review of metabolism, benefits and side effects. Life Sci. 1995;57(3):195-206.
6. Lu H, Li J, Zhang D, Stoner GD, Huang C. Molecular mechanisms involved in chemoprevention of black raspberry extracts: from transcription factors to their target genes. Nutr Cancer. 2006;54(1):69-78.
7. Schauss AG, Wu X, Prior RL, Ou B, Patel D, Huang D, Kababick JP. Phytochemical and nutrient composition of the freeze-dried amazonian palm berry, Euterpe oleraceae mart. (acai).
J Agric Food Chem. 2006 Nov 1;54(22):8598-603.
8. Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E. Antioxidant capacity and other bioactivities of the freeze-dried amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8604-10.
9. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol. 2006 Jan;39(1):44-84.

About the Author. Paul M. Gross, Ph.D., received his doctorate in physiology from the University of Glasgow, Scotland and was a post-doctoral fellow in neuroscience at the Laboratory of Cerebral Metabolism, National Institutes of Health, Bethesda, MD. A former Research Scholar for the Heart and Stroke Foundation of Ontario, he published 85 peer-reviewed journal reports and book chapters over a 25 year career in medical science, and was recipient of the Karger Memorial Award, Switzerland, for publications on brain capillaries. Dr. Gross is on the Steering Committee of the International Berry Health Association. He is senior author of a 2006 book on the goji berry entitled Wolfberry: Nature’s Bounty of Nutrition and Health (Booksurge Publishing, Amazon.com, http://wolfberry.org) and is publisher of The Berry Doctor's Journal, http://berrydoctor.com where the public can obtain free information on berry science and nutrition.